Latanoprost Ophthalmic

What is latanoprost?

Latanoprost (brand names: Xalatan®, Monoprost®, Xelpros®) is a prostaglandin used to reduce pressure in the eye and treat glaucoma.

Its use in dogs and other animals to treat glaucoma is off label (extra label). Many drugs are commonly prescribed for off-label use in veterinary medicine. 

“Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.

How is latanoprost given?

• Latanoprost is applied to the eye in the form of a liquid solution.
• Wash your hands before administering this medication.
• Do not touch the tip of the dropper to the surface of the eye or any other surface.
• Give this medication at least 5 minutes apart from other medications used in the eye.
• Wipe off excess medication on the face with a damp cloth or tissue.
• Do not give this medication to your pet if it is cloudy or changes color.
• DO NOT handle this medication if you are pregnant; if it is necessary, wear gloves and wash hands immediately after administering.

This medication should take effect within 1 to 2 hours; however, effects may not be noted outwardly, so laboratory tests may be needed to evaluate this medication’s effectiveness.

What if I miss giving my pet the medication?

If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.

Are there any potential side effects?

Latanoprost ophthalmic may cause the following side effects:

• A burning or stinging sensation
• Mild eye redness
• Growth of eyelashes
• Color change of the iris or around the eye

Serious adverse reactions may occur. If any of the following signs develop, stop giving latanoprost ophthalmic and contact your veterinarian immediately:

• Difficulty breathing
• Facial swelling
• Bright light sensitivity
• Severe redness in the eyes

This short-acting medication should stop working within 24 hours.

Are there any risk factors for this medication?

DO NOT USE in:

• Pets that are allergic to it
• Pets with eye inflammation (uveitis)

USE WITH CAUTION in:

• Pets at risk for lens luxation/subluxation
• Pets with liver disease or kidney disease
• Pets that are pregnant or nursing
• Pets that are going to have surgery

Are there any drug interactions I should be aware of?

There are no documented drug interactions for latanoprost ophthalmic. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this medication?

• Your veterinarian may monitor your pet to be sure that the medication is working by monitoring eye pressures.
• At home, monitor for any side effects such as those noted above. If any occur, stop using the medication and contact your veterinarian.

How do I store latanoprost ophthalmic?

• Store unopened bottles of this medication in the refrigerator between 36°F and 46°F (2°C and 8°C), protected from freezing.
• Store open bottles at room temperature up to 77°F (25°C) for 6 weeks.
• Protect from light.
• Keep the container out of reach of children and pets. 

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet’s weight and symptoms.